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Sophie Cai, Theodore S. Hong, Saveli I. Goldberg, Carlos Fernandez-del Castillo, Sarah P. Thayer, Cristina R. Ferrone, David P. Ryan, Lawrence S. Blaszkowsky, Eunice L. Kwak, Christopher G. Willett, Keith D. Lillemoe, Andrew L. Warshaw and Jennifer Y. Wo Updated long-term outcomes and prognostic factors for patients with unresectable locally advanced pancreatic cancer treated with intraoperative radiotherapy at the Massachusetts General Hospital, 1978 to 2010 Cancer 119

Version of Record online: 4 SEP 2013 | DOI: 10.1002/cncr.28329

Among 194 patients with unresectable locally advanced pancreatic cancer who received intraoperative radiotherapy as part of their treatment, the 1-year, 2-year, 3-year, and 5-year overall survival rates were 49%, 16%, 6%, and 3%, respectively. Small tumor diameter, low Charlson age-comorbidity index, and receipt of chemotherapy were found to be independently predictive of improved survival, with a median overall survival of 21.2 months for patients with all 3 favorable prognostic factors.

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