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Ethan Basch, Ann Marie Trentacosti, Laurie B. Burke, Virginia Kwitkowski, Robert C. Kane, Karen A. Autio, Elektra Papadopoulos, James P. Stansbury, Paul G. Kluetz, Harry Smith, Robert Justice and Richard Pazdur Pain palliation measurement in cancer clinical trials: The US Food and Drug Administration perspective Cancer 120

Version of Record online: 5 DEC 2013 | DOI: 10.1002/cncr.28470

Pain is an important endpoint in cancer clinical trials but is methodologically challenging to measure. This article provides the perspective of the US Food and Drug Administration regarding pain palliation measurement, with examples from past industry applications.

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