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Simone Hettmer, Natasha M. Archer, Gino R. Somers, Ana Novokmet, Amy J. Wagers, Lisa Diller, Carlos Rodriguez-Galindo, Lisa A. Teot and David Malkin Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers Cancer 120

Version of Record online: 30 DEC 2013 | DOI: 10.1002/cncr.28507

Children with germline TP53 mutations are predisposed to develop anaplastic rhabdomyosarcoma at a young age. Extension of the current Chompret criteria for Li-Fraumeni syndrome to include children with anaplastic rhabdomyosarcoma irrespective of family history should be considered.

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