Alexis D. Leal, Rui Qin, Pamela J. Atherton, Paul Haluska, Robert J. Behrens, Charles H. Tiber, Patanit Watanaboonyakhet, Matthias Weiss, Paul T. Adams, Travis J. Dockter, Charles L. Loprinzi and for the Alliance for Clinical Trials in Oncology North Central Cancer Treatment Group/Alliance trial N08CA—the use of glutathione for prevention of paclitaxel/carboplatin-induced peripheral neuropathy: A phase 3 randomized, double-blind, placebo-controlled study Cancer 120
Article first published online: 11 MAR 2014 | DOI: 10.1002/cncr.28654
Glutathione is not effective in preventing paclitaxel/carboplatin-induced peripheral neuropathy. In addition, it does not appear to interfere with the antitumor activity of paclitaxel/carboplatin.
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