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Hiroto Inaba, Aditya H. Gaur, Xueyuan Cao, Patricia M. Flynn, Stanley B. Pounds, Viswatej Avutu, Lindsay N. Marszal, Scott C. Howard, Ching-Hon Pui, Raul C. Ribeiro, Randall T. Hayden and Jeffrey E. Rubnitz Feasibility, efficacy, and adverse effects of outpatient antibacterial prophylaxis in children with acute myeloid leukemia Cancer 120

Article first published online: 26 MAR 2014 | DOI: 10.1002/cncr.28688

Outpatient intravenous antibiotic prophylaxis reduces the incidence of clinically or microbiologically documented infection and bacteremia, especially viridans streptococcal bacteremia, in children receiving treatment for acute myeloid leukemia. However, vancomycin-resistant enterococcal bacteremia has been documented in patients receiving antibiotic prophylaxis, and approaches to minimize resistance should be explored.

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