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Mingchuan Zhao, Yishi Zhang, Weijing Cai, Jiayu Li, Fei Zhou, Ningning Cheng, Ruixin Ren, Chao Zhao, Xuefei Li, Shengxiang Ren, Caicun Zhou and Fred R. Hirsch The Bim deletion polymorphism clinical profile and its relation with tyrosine kinase inhibitor resistance in Chinese patients with non–small cell lung cancer Cancer 120

Article first published online: 15 APR 2014 | DOI: 10.1002/cncr.28725

In this study, the incidence of a Bim deletion polymorphism is approximately 13%, and it is associated with a poor clinical response to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in Chinese patients who have EGFR mutations.

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