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Martin Schramm, Christian Wrobel, Ingmar Born, Marietta Kazimirek, Natalia Pomjanski, Marina William, Rainer Kappes, Claus Dieter Gerharz, Stefan Biesterfeld and Alfred Böcking Equivocal cytology in lung cancer diagnosis Cancer Cytopathology 119

Version of Record online: 16 MAR 2011 | DOI: 10.1002/cncy.20142

To a great extent, equivocal cytology in lung cancer diagnosis can be overcome by applying adjuvant multicolor FISH, DNA-image cytometry, or quantitative promoter hypermethylation analysis, reaching sensitivities of 78%, 79%, and 49.6% in the study population, respectively (specificities, 98.2%, 98.2%, and 98.4%, respectively). A new diagnostic algorithm is presented.

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