Marion F. Haug, Matthias Gesemann, Thomas Mueller and Stephan C.F. Neuhauss Phylogeny and expression divergence of metabotropic glutamate receptor genes in the brain of zebrafish (Danio rerio) Journal of Comparative Neurology 521
We describe the cloning, phylogenetic analysis and mRNA distribution of zebrafish metabotropic glutamate receptor genes (mGluRs). The 13 zebrafish mglur genes display well defined expression domains in the central nervous system, most prominently in the olfactory bulb, optic tectum, hypothalamus, cerebellum, and retina. Expression of paralogous genes shows both overlapping and complementary expression, suggesting sub- and/or neofunctionalization. Expression of group I mglurs revealed comparable patterns in larval and adult brains, suggesting similar functions at different developmental stages.
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