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Buntaro Zempo, Shinji Kanda, Kataaki Okubo, Yasuhisa Akazome and Yoshitaka Oka Anatomical distribution of sex steroid hormone receptors in the brain of female medaka Journal of Comparative Neurology 521

Article first published online: 4 APR 2013 | DOI: 10.1002/cne.23255

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Estrogen receptors (ERs) and androgen receptors (ARs) play crucial roles in coordinating reproductive functions. However, the distribution of these receptors has not been fully analyzed anatomically in the teleost brain. We analyzed the distribution of ERα, ERβ1, ERβ2, ARα, and ARβ mRNA by in situ hybridization in the brain of female medaka. All subtypes were expressed in the preoptic area and some other regions that are known to be involved in the regulation of sexual behavior or the hypothalamo-pituitary-gonadal axis.

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