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Anan A. Harbid, Bernie J. McLeod, Alain Caraty and Greg M. Anderson Seasonal changes in RFamide-related peptide-3 neurons in the hypothalamus of a seasonally breeding marsupial species, the brushtail possum (Trichosurus vulpecula) Journal of Comparative Neurology 521

Article first published online: 17 JUL 2013 | DOI: 10.1002/cne.23328

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RFRP-3 exhibits a pronounced seasonal fluctuation in cell numbers in the brushtail possum hypothalamus, suggesting an increased inhibitory tone during the non-breeding season. The lack of RFRP-3 fibers in the median eminence and of Fluoro-Gold uptake from the periphery imply its actions occur centrally rather than at the pituitary gland.

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