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Daniel Lindberg, Peilin Chen and Chien Li Conditional viral tracing reveals that steroidogenic factor 1-positive neurons of the dorsomedial subdivision of the ventromedial hypothalamus project to autonomic centers of the hypothalamus and hindbrain Journal of Comparative Neurology 521

Version of Record online: 25 JUL 2013 | DOI: 10.1002/cne.23338

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Using conditional adenoviral tracer combined with transgenic mice expressing Cre recombinase in the hypothalamic ventromedial nucleus (VMH), the present study shows that neurons in the VMH project to discrete areas in the brainstem including the parabrachial nucleus, rostral ventrolateral medulla, retrotrapezoid nucleus, and nucleus of the solitary tract. This study thus provides an anatomical basis for the possibility that VMH neurons may modulate autonomic activity via direct efferent inputs into the autonomic centers in the brainstem.

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