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Damien Isèbe and Philippe Nérin Numerical simulation of particle dynamics in an orifice–electrode system. Application to counting and sizing by impedance measurement International Journal for Numerical Methods in Biomedical Engineering 29

Version of Record online: 12 NOV 2012 | DOI: 10.1002/cnm.2528

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In most cases, counting and sizing of biological cells are based on electrical gating through a microorifice in a close orifice-electrode system that we don't experimentally apprehend. In this framework, we have developed a complete numerical approach to compute the exact particle size distribution by taking into account the trajectory and the orientation of the particles through the microorifice. This numerical approach is fully innovative in diagnosis engineering and can be used to perform particle sizing measurement by optimizing shape design or fluidic conditions.

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