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David C. Barber, Isra Valverde, Yubing Shi, Alistair Brown, Philipp Beerbaum and D. Rodney Hose Derivation of aortic distensibility and pulse wave velocity by image registration with a physics-based regularisation term International Journal for Numerical Methods in Biomedical Engineering 30

Article first published online: 10 OCT 2013 | DOI: 10.1002/cnm.2589

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Reliable estimates of aortic distensibility and pulse wave velocity and their variation along the axis of the vessel can be derived by registration of time series images using a regularisation term based on the one-dimensional wave equation. Validation is from numerical phantom data, and results are presented from clinical images for six cases of mild aortic coarctation.

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