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Jan Vogelsang, Christian Steinhauer, Carsten Forthmann, Ingo H. Stein, Britta Person-Skegro, Thorben Cordes and Philip Tinnefeld Make them Blink: Probes for Super-Resolution Microscopy ChemPhysChem 11

Article first published online: 14 JUL 2010 | DOI: 10.1002/cphc.201000189

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Make them blink: Switching fluorescent molecules between a bright and a dark state is essential to super-resolution. Different switching mechanisms (see picture) and their applicability for super-resolution microscopy with a focus on electron transfer based switching are discussed. Furthermore, factors that influence the resolution and present calibration methods for super-resolution microscopy are outlined.

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