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Dr. Yang Wei, Aby A. Thyparambil and Prof. Dr. Robert A. Latour Peptide–Surface Adsorption Free Energy Comparing Solution Conditions Ranging from Low to Medium Salt Concentrations ChemPhysChem 13

Version of Record online: 5 OCT 2012 | DOI: 10.1002/cphc.201200527

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Multi-technique methods involving surface plasmon resonance spectroscopy and atomic force microscopy provide experimental data for the characterization of peptide adsorption on self-assembled monolayers. A comparative study is carried out in phosphate-buffered saline (PBS) and potassium phosphate-buffered (PPB) water to determine the influence of the salt concentration on the adsorption behavior (see figure; ΔG0ads: free energy of peptide adsorption, Fdes: force required for peptide desorption).

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