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Lingye Yang, Min Zhao, Ruichen Zhang, Jie Dong, Ting Zhang, Prof. Dr. Xiaowei Zhan and Prof. Dr. Guojie Wang Synthesis and Fluorescence Study of a Quaternized Copolymer Containing Pyrene for DNA-Hybridization Detection ChemPhysChem 13

Article first published online: 5 NOV 2012 | DOI: 10.1002/cphc.201200765

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Built-in detector: A quaternized copolymer containing pyrene is described, which can bind to single-stranded DNA by electrostatic interactions to form a novel complex probe for the detection of DNA hybridization through strengthened fluorescence quenching through its intercalation into double-stranded DNA (see figure).

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