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Dr. Charles Esnault, Prof. Benoît Chénais, Dr. Nathalie Casse, Dr. Nicolas Delorme, Prof. Guy Louarn and Prof. Jean-François Pilard Electrochemically Modified Carbon and Chromium Surfaces for AFM Imaging of Double-Strand DNA Interaction with Transposase Protein ChemPhysChem 14

Article first published online: 4 JAN 2013 | DOI: 10.1002/cphc.201200885

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Caught by the tip: It is possible to study protein–DNA interactions even with long dsDNA molecules using modified chrome surfaces (see picture). Due to the immobilization of the DNA by one extremity only, the studies of the DNA–protein interactions on the surface are closer to biological reality.

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