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Björn Johansson, Prof. Fredrik Höök, Prof. David Klenerman and Dr. Peter Jönsson Label-Free Measurements of the Diffusivity of Molecules in Lipid Membranes ChemPhysChem 15

Article first published online: 8 JAN 2014 | DOI: 10.1002/cphc.201301136

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Hydrodynamic forces and imaging ellipsometry: The localized force of liquid flow through a micropipette is used to accumulate molecules bound to a lipid bilayer. When the flow is turned off, the molecules diffuse away, and this process is studied with surface-enhanced ellipsometric contrast (SEEC) imaging, which yields the mobility of the molecules without the use of labels (see picture).

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