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Dr. Archan Dey, Chris. J. van den Hoogen, Dr. Michel Rosso, Niek Lousberg, Marco M. R. M. Hendrix, Dr. Heiner Friedrich, Joaquín Ramírez-Rico, Prof. Han Zuilhof, Prof. Gijsbertus de With and Dr. Nico A. J. M. Sommerdijk Biomimetic Mineralization of Calcium Phosphate on a Functionalized Porous Silicon Carbide Biomaterial ChemPlusChem 77

Version of Record online: 23 JUL 2012 | DOI: 10.1002/cplu.201200118

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Make no bones about it: To achieve porous bioactive implant materials for load-bearing bone, a new strategy towards biomimetic calcium phosphate coatings has been investigated. The surface of the porous silicon carbide is modified with a covalently bound monolayer exposing carboxylic acid groups that promote the selective deposition of a very well-defined fully crystalline layer of oriented mixed octacalcium phosphate/hydroxyapatite crystals on substrates with complex geometry (see figure).

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