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Monika Schaffarczyk, Prof. Teodor Silviu Balaban, Prof. Michael Rychlik and Prof. Andrea Buettner Syntheses of Chiral 1,8-Cineole Metabolites and Determination of Their Enantiomeric Composition in Human Urine After Ingestion of 1,8-Cineole-Containing Capsules ChemPlusChem 78

Version of Record online: 18 DEC 2012 | DOI: 10.1002/cplu.201200253

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Biotransformation of odorants and volatiles in humans is essential for understanding their potential roles with regard to physiological action. Eucalyptol, a common odorant, is shown to yield a range of chiral metabolites that are detectable in human urine, thereby revealing information on rarely investigated pathways in human metabolism (see figure).

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