Constanze Hartmann, Dr. Annika Triller, Prof. Dr. Marc Spehr, Prof. Dr. Ralf Dittrich, Prof. Dr. Hanns Hatt and Prof. Dr. Andrea Buettner Sperm-Activating Odorous Substances in Human Follicular Fluid and Vaginal Secretion: Identification by Gas Chromatography–Olfactometry and Ca2+ Imaging ChemPlusChem 78
Find the egg: Before contact, egg and sperm communicate by chemotaxis. Chemoreceptors expressed on sperm seem to play a key role in this communication (see figure). Several odor-active ligands for such receptors have been reported in the past, but were exclusively of synthetic origin. Herein, the first endogenous odor-active ligands are identified in bodily fluids of the female reproductive tract.
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