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Dr. Honghua Jia, Chao Zhong, Fan Huang, Chunming Wang, Lisha Jia, Dr. Hua Zhou and Dr. Ping Wei The Preparation and Characterization of a Laccase Nanogel and Its Application in Naphthoquinone Synthesis ChemPlusChem 78

Article first published online: 4 APR 2013 | DOI: 10.1002/cplu.201300066

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It′s a wrap: The amino groups of lysine in laccase were modified with N-acryloxysuccinimide (NAS). Acrylamide was then added to the modified laccase molecule through hydrogen bonds to form a modified-laccase molecule–acrylamide assembly, followed by polymerization in situ through addition of ammonium persulfate (APS) and tetramethylethylenediamine (TEMED) to produce a laccase nanogel encapsulated in polyacrylamide (see scheme).

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