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Dr. Fang Pu, Xia Liu, Xinjian Yang, Zhen Liu, Prof. Dr. Jinsong Ren, Prof. Dr. Shu Wang and Prof. Dr. Xiaogang Qu Versatile Fluorescent Conjugated Polyelectrolyte-Capped Mesoporous Silica Nanoparticles for Controlled Drug Delivery and Imaging ChemPlusChem 78

Article first published online: 13 MAY 2013 | DOI: 10.1002/cplu.201300135

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Luminescent cap: The properties of a fluorescent conjugated polyelectrolyte and mesoporous silica nanoparticles have been combined to prepare a pH-controlled drug delivery and cellular imaging system by using a simple and general method (see scheme). The fluorescent conjugated polyelectrolyte was used as both the capping agent and the imaging probe with low cytotoxicity. It is a promising candidate for simultaneous diagnostics and therapeutics.

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