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Dr. Ivan Rehor, Dr. Hana Mackova, Dr. Sergey K. Filippov, Dr. Jan Kucka, Dr. Vladimir Proks, Jitka Slegerova, Dr. Stuart Turner, Prof. Gustaaf Van Tendeloo, Dr. Miroslav Ledvina, Dr. Martin Hruby and Dr. Petr Cigler Fluorescent Nanodiamonds with Bioorthogonally Reactive Protein-Resistant Polymeric Coatings ChemPlusChem 79

Version of Record online: 11 DEC 2013 | DOI: 10.1002/cplu.201300339

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A shining example: Fluorescent nanodiamonds were coated by a thin layer of methacrylate copolymer enabling high-yield attachment of molecules by click chemistry (see scheme). The particles are protein-resistant and extremely colloidally stable in buffers and biological media. The polymer fully preserves the unique optical properties of the fluorescent nitrogen-vacancy centers that are crucial for bioimaging applications.

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