Jing Wu, Pieter Eduard, Dr. Shanmugam Thiyagarajan, Dr. Jacco van Haveren, Dr. Daan S. van Es, Prof. Dr. Cor E. Koning, Dr. Martin Lutz and Dr. Célia Fonseca Guerra Isohexide Derivatives from Renewable Resources as Chiral Building Blocks ChemSusChem 4
Hextended family: A new family of C2/C5 carbon-extended isohexide derivatives is synthesized in a stereo-controlled manner with high purity and good yield. These chiral and rigid biobased building blocks can be widely applied: in pharmaceuticals, cholesteric liquid crystals, and as building blocks for high-performance polymers. The isoidide-based diacid is a potential renewable alternative to terephthalic acid.
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