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Dr. Anna Tsoukala, Dr. Ludmila Peeva, Prof. Andrew G. Livingston and Prof. Hans-René Bjørsvik Separation of Reaction Product and Palladium Catalyst after a Heck Coupling Reaction by means of Organic Solvent Nanofiltration ChemSusChem 5

Version of Record online: 12 DEC 2011 | DOI: 10.1002/cssc.201100355

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Squeezing products through holes: We have successfully developed an organic solvent nanofiltration process for the separation of [Pd(PPh3)OAc] from the products found in a Heck coupling postreaction mixture. A quantitative recovery of the products is achieved in a purity that meets the health and safety specifications for pharmaceutical products by using a commercially available membrane.

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