E-mail a Wiley Online Library Link

Dr. Aditya L. Gottumukkala, Jasmin Suljagic, Dr. Kiran Matcha, Prof. Dr. Johannes G. de Vries and Prof. Dr. Adriaan J. Minnaard Efficient Formation of Benzylic Quaternary Centers via Palladium Catalysis ChemSusChem 6

Version of Record online: 2 JUL 2013 | DOI: 10.1002/cssc.201300276

Thumbnail image of graphical abstract

Four′s a crowd: An efficient protocol for the formation of benzylic quaternary centers via arylation of enones using a catalyst made from Pd(O2CCF3)2 and 2,2′-bipyridine is developed. For cyclic substrates, catalyst loadings as low as 1 mol % Pd are enough to afford excellent yields (>90 %) using a variety of arylboronic acids. In case of acyclic substrates, the addition of KSbF6 was found to improve conversions and yields.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field