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Elmorsy Khaled, H. N. A. Hassan, Gehad G. Mohamed and Aly Eldin A. Seleim Towards disposable sensors for drug quality control: Dextromethorphan screen- printed electrodes Drug Testing and Analysis 2

Article first published online: 13 SEP 2010 | DOI: 10.1002/dta.159

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A simple, rapid, reliable and reproducible method for mass production of disposable sensors using screen-printing technology is described. The fabricated bi-electrode potentiometric strip containing both working and reference electrode was used as dextromethorphan (DXM) sensor. The proposed sensors worked satisfactorily in the concentration range from 10−5 to 10−2 mol L−1 with detection limit reaching 6 × 10−6 mol L−1 and adequate shelf lifetime of 8 months. DXM was determined in pharmaceutical formulations under batch and flow injection analysis (FIA) conditions with sampling output 120 h−1.

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