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Walid D. Fakhouri, Lindsey Rhea, Tianli Du, Eileen Sweezer, Harris Morrison, David Fitzpatrick, Baoli Yang, Martine Dunnwald and Brian C. Schutte MCS9.7 enhancer activity is highly, but not completely, associated with expression of Irf6 and p63 Developmental Dynamics 241

Article first published online: 23 NOV 2011 | DOI: 10.1002/dvdy.22786

Key findings:

  • MCS9.7 activity is highly associated with endogenous expression of IRF6 in most embryonic murine tissues.

  • MCS9.7 is not sufficient to recapitulate the expression of IRF6 in the medial edge epithelium at E14.5.

  • MCS9.7 activity and IRF6 expression are highly colocalized in periderm where p63 is absent in orofacial epithelium.

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