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Timothy J. Mead and Katherine E. Yutzey Notch pathway regulation of neural crest cell development in vivo Developmental Dynamics 241

Version of Record online: 3 JAN 2012 | DOI: 10.1002/dvdy.23717

Key findings:

  • Altered Notch signaling in neural crest cells results in neurocristopathies.

  • Manipulation of Notch signaling results in defective neural crest cell migration.

  • Notch signaling promotes neural crest cell proliferation.

  • Notch signaling regulates pharyngeal arch artery smooth muscle differentiation.

  • Notch signaling promotes gliogenesis while inhibiting neurogenesis.

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