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Mingi Hong, Karen A. Schachter, Guoying Jiang and Robert S. Krauss Neogenin regulates sonic hedgehog pathway activity during digit patterning Developmental Dynamics 241

Article first published online: 14 FEB 2012 | DOI: 10.1002/dvdy.23745

Key findings:

  • Neo1 mutant mice have preaxial polydactyly with low penetrance.

  • Neo1 interacts genetically with Gli3 in a complex manner.

  • Neogenin regulates SHH signaling in vivo and in vitro.

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