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Elisabet Wallgard, Anja Nitzsche, Jimmy Larsson, Xiaoyuan Guo, Lothar C. Dieterich, Anna Dimberg, Tommie Olofsson, Fredrik C. Pontén, Taija Mäkinen, Mattias Kalén and Mats Hellström Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development Developmental Dynamics 241

Article first published online: 21 FEB 2012 | DOI: 10.1002/dvdy.23753

Key findings:

  • Paladin, a putative phosphatase, is expressed in the vasculature.

  • During angiogenesis Paladin is expressed in endothelial cells of veins and capillaries.

  • In certain mature vessels, Paladin expression is shifted to vascular smooth muscle cells of arteries.

  • Paladin expression is reactivated during pathological tumor angiogenesis in the adult.

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