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Dion Giovannone, Michelle Reyes, Rachel Reyes, Lisa Correa, Darwin Martinez, Hannah Ra, Gustavo Gomez, Joshua Kaiser, Le Ma, Mary-Pat Stein and Maria Elena de Bellard Slits affect the timely migration of neural crest cells via robo receptor Developmental Dynamics 241

Version of Record online: 23 JUN 2012 | DOI: 10.1002/dvdy.23817

Key findings:

  • Pre-migratory neural crest expresses Slit molecules.

  • Slit molecules affect cell cytoskeleton via Robo receptor.

  • Neural crest cells cytoskeleton is re-arranged, cells become less migratory.

  • Neural crest cells will not delaminate.

  • Slit delays crest EMT.

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