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Akiko Obinata and Yoshihiro Akimoto Effects of retinoic acid and Gbx1 on feather-bud formation and epidermal transdifferentiation in chick embryonic cultured dorsal skin Developmental Dynamics 241

Version of Record online: 30 JUL 2012 | DOI: 10.1002/dvdy.23834

Key Findings:

  • Gbx1 is involved in feather-bud formation.

  • Retinoic acid inhibits feather-bud formation, induces transdifferentiation of epidermis to mucosal epithelium, and increases Gbx1 expression.

  • Transfection of the epidermis with Gbx1 cDNA induces elongation of the feather bud, but does not induce transdifferentiation.

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