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Sabine Freter, Yuko Muta, Paul O'Neill, Vassil S. Vassilev, Shigehiro Kuraku and Raj K. Ladher Pax2 modulates proliferation during specification of the otic and epibranchial placodes Developmental Dynamics 241

Article first published online: 25 SEP 2012 | DOI: 10.1002/dvdy.23856

Key Findings

  • Neither suppression nor over-expression of Pax2 affects the extent of the precursor region of the inner ear and epibranchial placodes, the PPA.

  • Suppressing and over-expressing Pax2 does affect the differentiation of the inner ear and the epibranchial placodes.

  • Pax2 suppression reduces proliferation of PPA precursors.

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