Dorothy E. Pazin, Laura W. Gamer, Karen A. Cox and Vicki Rosen Molecular profiling of synovial joints: Use of microarray analysis to identify factors that direct the development of the knee and elbow Developmental Dynamics 241
Version of Record online: 25 SEP 2012 | DOI: 10.1002/dvdy.23861
How individual joints acquire unique shapes and specialized structures is unknown.
There are fundamental difference in the way joints develop after interzone formation.
We use comparative gene expression to identify knee and elbow genes.
TGFβ regulates knee development.
Muscle development regulates elbow morphogenesis.
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