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Koichiro Ichimura, Yayoi Fukuyo, Tomomi Nakamura, Rebecca Powell, Tatsuo Sakai and Tomoko Obara Structural disorganization of pronephric glomerulus in Zebrafish mpp5a/nagie oko mutant Developmental Dynamics 241

Version of Record online: 25 OCT 2012 | DOI: 10.1002/dvdy.23877

Key Findings:

  • Mpp5a is localized at the podocyte foot process in the zebrafish pronephric glomerulus.

  • Zebrafish mpp5am520 mutants display structural disorganization of the pronephric glomerulus including glomerular capillary agenesis, but regular foot processes with slit diaphragm were formed.

  • Mpp5a is not prerequisite to form podocyte slit diaphragm in the pronephric glomerular development in zebrafish.

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