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Koichiro Ichimura, Yayoi Fukuyo, Tomomi Nakamura, Rebecca Powell, Tatsuo Sakai and Tomoko Obara Structural disorganization of pronephric glomerulus in Zebrafish mpp5a/nagie oko mutant Developmental Dynamics 241
Article first published online: 25 OCT 2012 | DOI: 10.1002/dvdy.23877
Key Findings:
Mpp5a is localized at the podocyte foot process in the zebrafish pronephric glomerulus.
Zebrafish mpp5am520 mutants display structural disorganization of the pronephric glomerulus including glomerular capillary agenesis, but regular foot processes with slit diaphragm were formed.
Mpp5a is not prerequisite to form podocyte slit diaphragm in the pronephric glomerular development in zebrafish.
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