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Basile Tarchini, Christine Jolicoeur and Michel Cayouette In vivo evidence for unbiased ikaros retinal lineages using an ikaros-cre mouse line driving clonal recombination Developmental Dynamics 241

Article first published online: 5 NOV 2012 | DOI: 10.1002/dvdy.23881

Key Findings

  • The Ikaros retinal lineage gives rise to both early- and late-born cell types and is confirmed unbiased in vivo

  • One Ikaros-Cre mouse line allows sparse recombination in retinal progenitors and is validated as a tool for in vivo lineage tracing

  • A distinct Ikaros-Cre mouse line allows sparse recombination specifically in some postmitotic early-born retinal cell types

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