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Young-Hoon Lee, Allison Williams, Chang-Soo Hong, Youngjae You, Makoto Senoo and Jean-Pierre Saint-Jeannet Early development of the thymus in Xenopus laevis Developmental Dynamics 242

Article first published online: 5 DEC 2012 | DOI: 10.1002/dvdy.23905

Key Findings:

  • The thymus primordia arise from the second pharyngeal pouch.
  • Thymus formation is independent of hoxa3 expression in the pouch endoderm.
  • foxn1 expression correlates with the initiation of thymic epithelial differentiation.
  • Neural crest cells are not required for thymus specification or T-cell differentiation.

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