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Sam Kwiatkowski, Ravi P. Munjaal, Teresa Lee and Peter Y. Lwigale Expression of pro- and anti-angiogenic factors during the formation of the periocular vasculature and development of the avian cornea Developmental Dynamics 242

Version of Record online: 24 APR 2013 | DOI: 10.1002/dvdy.23956

Key findings

  • Angioblasts migrate into the periocular region of the eye during development, but avoid the presumptive cornea.
  • Pro- and anti-angiogenic factors are expressed within the vicinity of the developing cornea, whereas angioblasts, periocular mesenchyme and forming ocular vasculature express their receptors.
  • Expression profile of pro- and anti-angiogenic factors and their receptors suggest their potential roles in ocular vasculogenesis and corneal avascularity during development.

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