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Y. Blech-Hermoni, S.J. Stillwagon and A.N. Ladd Diversity and conservation of CELF1 and CELF2 RNA and protein expression patterns during embryonic development Developmental Dynamics 242

Article first published online: 15 APR 2013 | DOI: 10.1002/dvdy.23959

Key Findings

  • Developmental regulation of CELF1 and CELF2 protein dynamics is independent of transcript levels in the embryonic heart.
  • CELF1 and CELF2 transcripts are largely co-expressed, but are found in mutually exclusive territories in several tissues.
  • Several tissue- and subcellular compartment-specific isoforms of CELF1 and CELF2 proteins suggest a means for functional diversity and specificity for these proteins.
  • CELF1 and CELF2 expression patterns are largely conserved between chicken and mouse embryos.

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