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Swapnalee Sarmah and James A. Marrs Complex cardiac defects after ethanol exposure during discrete cardiogenic events in zebrafish: Prevention with folic acid Developmental Dynamics 242

Version of Record online: 2 SEP 2013 | DOI: 10.1002/dvdy.24015

Key Findings

  • Zebrafish FASD model showed that ethanol interrupts multiple steps of cardiogenesis.
  • Ethanol exposure during zebrafish cardiogenesis produces persistent heart defects.
  • Chronic ethanol exposure during cardiogenesis produces complex cardiac defects.
  • Retinoic acid co-supplementation partially rescues ethanol-induced cardiac defects.
  • Folic acid co-supplementation prevents a wide spectrum of ethanol-induced heart defects.

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