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Nuala M. Mulgrew, Laura M.J. Kettyle, Joanne M. Ramsey, Susan Cull, Laura J. Smyth, Danielle M. Mervyn, Janet J. Bijl and Alexander Thompson c-Met inhibition in a HOXA9/Meis1 model of CN-AML Developmental Dynamics 243

Article first published online: 4 DEC 2013 | DOI: 10.1002/dvdy.24070

Key Findings

  • Altered gene, miR and protein expression in a HOXA9/Meis1 model of CN-AML
  • Identification and Molecular targeting of key pathways in CN-AML
  • c-Met inhibitor SU11274 demonstrates anti-leukemic activity in human and mouse AML cells

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