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Åsa Alexandra Borg, Sindre Andre Pedersen, Henrik Jensen and Helena Westerdahl Variation in MHC genotypes in two populations of house sparrow (Passer domesticus) with different population histories Ecology and Evolution 1

Version of Record online: 8 SEP 2011 | DOI: 10.1002/ece3.13

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Small populations are likely to have a low genetic ability for disease resistance due to loss of genetic variation through inbreeding and genetic drift. We evaluated inter- and intrapopulation variation in MHC genotypes between an inbred (Aldra) and a relatively outbred population (Hestmannøy) of house sparrows (Passer domesticus) in a metapopulation at Helgeland, Norway. Genomic (gDNA) and transcribed (cDNA) alleles of functional MHC class I and IIB loci, along with neutral noncoding microsatellite markers, were analyzed to obtain relevant estimates of genetic variation.

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