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Marcus Maschke, Max Lieb and Nils Metzler-Nolte Biologically Active Trifluoromethyl-Substituted Metallocene Triazoles: Characterization, Electrochemistry, Lipophilicity, and Cytotoxicity European Journal of Inorganic Chemistry 2012

Version of Record online: 30 OCT 2012 | DOI: 10.1002/ejic.201200798

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A series of new trifluoromethylated metallocene triazoles was synthesized using “click” chemistry (copper-catalyzed azide–alkyne cycloaddition). The new triazoles display suitable lipophilic character and exert promising antiproliferative activities against a range of cancer cell lines.

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