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Elena García-Moreno, Elena Cerrada, M. José Bolsa, Asunción Luquin and Mariano Laguna Water-Soluble Phosphanes Derived from 1,3,5-Triaza-7-phosphaadamantane and Their Reactivity towards Gold(I) Complexes European Journal of Inorganic Chemistry 2013

Article first published online: 13 FEB 2013 | DOI: 10.1002/ejic.201201411

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The synthesis of new water-soluble phosphanes derived from 1,3,5-triaza-7-phosphaadamantane and their reactivity towards gold(I) complexes is described. Strong antiproliferative effects are observed in some of the new compounds in the human ovarian carcinoma cell lines A2780 and its cisplatin-resistant variant (A2780cisR).

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