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Shida Miao, Lijing Sun, Ping Wang, Ruina Liu, Zhiguo Su and Songping Zhang Soybean oil-based polyurethane networks as candidate biomaterials: Synthesis and biocompatibility European Journal of Lipid Science and Technology 114

Article first published online: 10 JUL 2012 | DOI: 10.1002/ejlt.201200050

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A new class of biocompatible polyurethanes was prepared from soybean oil-based polyol which was synthesized by ring-opening reaction of epoxidized monoglyceride with lactic acid. The synthesized soybean oil-based polyurethanes have adjustable tensile strengths from 9.30 to 27.1 MPa and elongation at break of 74.1–110.7%. Mouse fibroblast cells (L-929) showed good adhesion and growth behavior on the polyurethane samples with more hydrophilic surfaces, and the cell viabilities of more than 50% were achieved with commercial tissue culture polystyrene disk as control.

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