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Lucia Chiummiento, Maria Funicello, Maria Teresa Lopardo, Paolo Lupattelli, Sabine Choppin and Françoise Colobert Concise Total Synthesis of Permethylated Anigopreissin A, a New Benzofuryl Resveratrol Dimer European Journal of Organic Chemistry 2012

Article first published online: 28 NOV 2011 | DOI: 10.1002/ejoc.201101422

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Facile access to permethylated anigopreissin A (1), a dimer of resveratrol, from methyl 3,5-dihydroxybenzoate is developed. The synthesis involves cross-coupling reactions (Sonogashira and Suzuki) and a Wittig olefination and is spread over eight steps.

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