Orit Harari-Steinberg, Sally Metsuyanim, Dorit Omer, Yehudit Gnatek, Rotem Gershon, Sara Pri-Chen, Derya D. Ozdemir, Yaniv Lerenthal, Tzahi Noiman, Herzel Ben-Hur, Zvi Vaknin, David F. Schneider, Bruce J. Aronow, Ronald S. Goldstein, Peter Hohenstein and Benjamin Dekel Identification of human nephron progenitors capable of generation of kidney structures and functional repair of chronic renal disease EMBO Molecular Medicine 5
Article first published online: 2 SEP 2013 | DOI: 10.1002/emmm.201201584
This study reports the first isolation of a NCAM1+ population of nephron progenitor cells that can be propagated, form tubules and integrate into kidneys of a mouse model of renal disease, suggesting therapeutic avenues in regenerative medicine.
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