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Yung-Luen Yu, Ruey-Hwang Chou, Woei-Cherng Shyu, Shu-Ching Hsieh, Chen-Shiou Wu, Shu-Ya Chiang, Wei-Jung Chang, Jia-Ni Chen, Yen-Ju Tseng, Yu-Hsuan Lin, Wei Lee, Su-Peng Yeh, Jennifer L. Hsu, Cheng-Chieh Yang, Shih-Chieh Hung and Mien-Chie Hung Smurf2-mediated degradation of EZH2 enhances neuron differentiation and improves functional recovery after ischaemic stroke EMBO Molecular Medicine 5

Version of Record online: 25 MAR 2013 | DOI: 10.1002/emmm.201201783

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Smurf2-mediated degradation of EZH2 enhances neuronal differentiation of human mesenchymal stem cells (hMSCs). This enables expression of PPARgamma in hMSCs, which when implanted improve recovery in a rat model of stroke.

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